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Histoplasma duboisii

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Title: Histoplasma duboisii  
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Subject: Histoplasma, African histoplasmosis
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Histoplasma duboisii

Histoplasma duboisii
Scientific classification
Kingdom: Fungi
Division: Ascomycota
Class: Eurotiomycetes
Order: Onygenales
Family: Ajellomycetaceae
Genus: Histoplasma
Species: H. duboisii
Binomial name
Histoplasma duboisii

Histoplasma capsulatum var. duboisii

(Vanbreus.) Cif.

Histoplasma duboisii is a species of fungi within the Ajellomycetaceae family. Formerly known as Histoplasma capsulatum var. duboisii,[1] [2] it is the causative agent of African histoplasmosis.[3]


  1. ^ Although the designation, "Histoplasma capsulatum var. duboisii," is still widely used in scientific literature, evidence for the name-change and elevation of H. duboisii to a species, comes from a genomic cladistics analysis, Kasuga, T; Taylor, JW; White, TJ (March 1999). "Phylogenetic relationships of varieties and geographical groups of the human pathogenic fungus Histoplasma capsulatum Darling". J Clin Microbiol 37 (3): 653–663. PMC 84508. PMID 9986828.  "Under a phylogenetic species concept based on possession of multiple shared derived characters, as well as concordance of four gene genealogies, H. capsulatum could be considered to harbor six species instead of three varieties."
  2. ^ Further support for the name-change comes from quantitative analysis of the gene expression products; "All the strains of H. capsulatum var. capsulatum RFLP classes II and III were grouped into two distinct clusters: the heterogenic RFLP class I formed a large, but also well-defined group, whereas the outgroup strains of H. capsulatum var. duboisii, B. dermatitidis, P. brasiliensis and S. schenckii were shifted away." Zarnowski, R; Miyazaki M; Dobrzyn A; Ntambi JM; Woods JP (June 2007). "Typing of Histoplasma capsulatum strains by fatty acid profile analysis". J Med Microbiol 56 (6): 788–797. PMC 2748824. PMID 17510264. doi:10.1099/jmm.0.47067-0. 
  3. ^ Gugnani HC (2000). "Histoplasmosis in Africa: a review". Indian J Chest Dis Allied Sci 42 (4): 271–77. PMID 15597674. 
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