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Title: D4  
Author: World Heritage Encyclopedia
Language: English
Subject: Kobret, Hemorphin, Naloxonazine, Naloxol, Gemazocine
Publisher: World Heritage Encyclopedia


Molecular formula C20H21D4NO4
Molar mass 347.42 g/mol
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)

6β-Naltrexol-d4 is an opioid 'neutral antagonist', in contrast to inverse-agonists often dubbed "antagonists" for simplicities sake, such as naloxone or naltrexone.[1] It is labeled with deuterium for NMR imaging.


  1. ^ The Relative Potency of Inverse Opioid Agonists and a Neutral Opioid Antagonist in Precipitated Withdrawal and Antagonism of Analgesia and Toxicity. Sunil Sirohi, Shveta V. Dighe, Priyanka A. Madia and Byron C. Yoburn

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