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Cirazoline

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Title: Cirazoline  
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Subject: Adrenergic receptor, Alpha-1 adrenergic receptor, Alpha-2 adrenergic receptor
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Cirazoline

Template:Chembox ChEMBL
Cirazoline
Identifiers
CAS number 59939-16-1
PubChem 2765
ChemSpider 2663 YesY
MeSH cirazoline
IUPHAR ligand 515
Jmol-3D images Image 1
Properties
Molecular formula C13H16N2O
Molar mass 216.279
 YesY (verify) (what is: YesY/N?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Cirazoline is a nonselective agonist of the alpha-1 adrenergic receptor (α1-AR), and an antagonist to the alpha-2 adrenergic receptor.[1] It is believed that this combination of properties could make cirazoline an effective vasoconstricting agent.[1]

Cirazoline has also been shown to decrease food intake in rats, purportedly through activation of α1-adrenoceptors in the paraventricular nucleus in the hypothalamus of the brain.[2]

References


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