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3,4-Ethylenedioxy-N-methylamphetamine (EDMA) is an entactogen drug of the amphetamine class.[1][2] It is an analogue of MDMA where the methylenedioxy ring has been replaced by an ethylenedioxy ring.[1][2] EDMA was first synthesized by Alexander Shulgin.[1] In his book PiHKAL, the dosage is listed as 150–250 mg, and the duration listed as 3–5 hours.[1] According to Shulgin, EDMA produces a bare threshold consisting of paresthesia, nystagmus, and hypnogogic imagery, with few to no other effects.[1] Scientific research has demonstrated that EDMA acts as a non-neurotoxic serotonin releasing agent with moderately diminished potency relative to MDMA, and with negligible effects on dopamine release.[2] Based on Shulgin's reports of essential inactivity at 150–250 mg, it may be more active at higher doses.
Entactogens: Lophophine
Amphetamine, Cocaine, Iron, Zinc, Methamphetamine
5-Methoxytryptamine, Metitepine, Lysergic acid diethylamide, Bromocriptine, Methysergide
5-Carboxamidotryptamine, Metitepine, Lysergic acid diethylamide, Bromocriptine, Methysergide
Amphetamine, Lysergic acid diethylamide, Methamphetamine, Iron, Zinc
Amphetamine, Methamphetamine, Lysergic acid diethylamide, Norepinephrine, Iron
Amphetamine, Lysergic acid diethylamide, Iron, Zinc, 5-Carboxamidotryptamine
Lysergic acid diethylamide, 5-Carboxamidotryptamine, 5-Methoxytryptamine, Metitepine, Amphetamine