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L-xylulose reductase

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Title: L-xylulose reductase  
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Subject: Xylitol, List of enzymes, Xylulose, List of EC numbers (EC 1)
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L-xylulose reductase

L-xylulose reductase
EC number IntEnz BRENDA ExPASy KEGG MetaCyc metabolic pathway
PRIAM PDB structures PDBsum
dicarbonyl/L-xylulose reductase
Symbol DCXR
Entrez HUGO OMIM RefSeq UniProt EC number Locus q25.3

In chemical reaction

xylitol + NADP+ \rightleftharpoons L-xylulose + NADPH + H+

Thus, the two substrates of this enzyme are xylitol and NADP+, whereas its 3 products are D-xylulose, NADPH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is xylitol:NADP+ 2-oxidoreductase (L-xylulose-forming).


A deficiency is responsible for pentosuria.


External links

  • Medical Subject Headings (MeSH)
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