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3-(2-Aminoethyl)phenol
m-Tyramine; 3-Tyramine; 3-Hydroxyphenylethylamine
Oc1cc(ccc1)CCN
InChI=InChI=1S/C8H11NO/c9-5-4-7-2-1-3-8(10)6-7/h1-3,6,10H,4-5,9H2
meta-Tyramine, also known as m-tyramine or 3-tyramine as well as 3-hydroxyphenylethylamine, is an endogenous monoamine compound and trace amine of the phenethylamine class.[1][2][3] It is a positional isomer of para-tyramine, and similarly to it, has effects on the adrenergic and dopaminergic systems.[4][5]
: PNS
* Note that many TCAs, TeCAs, antipsychotics, ergolines, and some piperazines like buspirone and trazodone all antagonize α1-adrenergic receptors as well, which contributes to their side effects such as orthostatic hypotension.
* Note that many atypical antipsychotics and azapirones like buspirone (via metabolite 1-PP) antagonize α2-adrenergic receptors as well.
* Note that MAO-B inhibitors also influence norepinephrine/epinephrine levels since they inhibit the breakdown of their precursor dopamine.
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