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para-Bromoamphetamine (PBA), also known as 4-bromoamphetamine (4-BA), is an amphetamine derivative which acts as a serotonin-norepinephrine-dopamine releasing agent (SNDRA) and produces stimulant effects.
Like most other para-substituted amphetamines, PBA is highly neurotoxic and produces long-term depletion of brain serotonin.[1]
* Note that many TCAs, TeCAs, antipsychotics, ergolines, and some piperazines like buspirone and trazodone all antagonize α1-adrenergic receptors as well, which contributes to their side effects such as orthostatic hypotension.
* Note that many atypical antipsychotics and azapirones like buspirone (via metabolite 1-PP) antagonize α2-adrenergic receptors as well.
* Note that MAO-B inhibitors also influence norepinephrine/epinephrine levels since they inhibit the breakdown of their precursor dopamine.
Entactogens: Lophophine
Amphetamine, Cathine, Cathinone, Chlorphentermine, Pseudoephedrine, Levomethamphetamine
5-Carboxamidotryptamine, 5-Methoxytryptamine, Metitepine, Lysergic acid diethylamide, Bromocriptine