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3(or 17)b-hydroxysteroid Dehydrogenase

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Title: 3(or 17)b-hydroxysteroid Dehydrogenase  
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Subject: List of EC numbers (EC 1)
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3(or 17)b-hydroxysteroid Dehydrogenase

17β-Hydroxysteroid dehydrogenase
EC number CAS number IntEnz BRENDA ExPASy KEGG MetaCyc metabolic pathway
PRIAM PDB structures PDBsum
Gene Ontology EGO

17β-Hydroxysteroid dehydrogenases (

Note that the major reactions catalysed by 17β-HSD (e.g., the conversion of androstenedione to testosterone) are in fact hydrogenation (reduction) rather than dehydrogenation (oxidation) reactions.


Genes coding for 17β-HSD include:

Clinical significance

Isozyme 3 is responsible for 17-beta-hydroxysteroid dehydrogenase deficiency.


  • Medical Subject Headings (MeSH)

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  • Medical Subject Headings (MeSH)
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