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Title: 77-lh-28-1  
Author: World Heritage Encyclopedia
Language: English
Subject: SIB-1553A, Sabcomeline, Pirisudanol, Alvameline, Xanomeline
Publisher: World Heritage Encyclopedia


IUPAC name
ChemSpider  YesY
Jmol-3D images Image
Molar mass 328.50 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
 YesY  (: YesY/N?)

77-LH-28-1 is a selective agonist of muscarinic acetylcholine receptor subtype 1 (M1) discovered in 2008. It is an allosteric agonist, exhibiting over 100-fold specificity for M1 over other muscarinic receptor subtypes. 77-LH-28-1 penetrates the brain by crossing the blood brain barrier and is therefore a useful pharmocologic tool with cognition enhancing effects.[1]


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