A-68,930

A-68930

IUPAC name

(1R,3S)-1-(Aminomethyl)-3-phenyl-3,4-dihydro-1H-isochromene-5,6-diol[1]

Identifiers
CAS number HCl) YesY
PubChem 122324 YesY
ChemSpider 109076 YesY
MeSH A+68930
Jmol-3D images Image 1
Properties
Molecular formula C16H17NO3
Molar mass 271.31 g mol−1
log P 1.175
Acidity (pKa) 9.491
Basicity (pKb) 4.506
 N (verify) (what is: YesY/N?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

A-68930 is a synthetic compound that acts as a selective dopamine receptor D1 partial agonist.[2][3] It is orally active and has antidepressant and anorectic effects in animals, producing wakefulness and tachycardia,[4][5][6][7] but without stimulant effects, instead producing sedation.[8][9] The difference in effects between A-68930 and other D1 agonists such as SKF-82958 may be due to their differing effects on the related D5 receptor.[10]

References



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