Adenosine monophosphate

Adenosine monophosphate (AMP), also known as 5'-adenylic acid, is a nucleotide that is used as a monomer in RNA. It is an ester of phosphoric acid and the nucleoside adenosine. AMP consists of a phosphate group, the sugar ribose, and the nucleobase adenine. As a substituent it takes the form of the prefix adenylyl-.

Production and degradation

AMP can be produced during ATP synthesis by the enzyme adenylate kinase by combining two ADP molecules:

2 ADP → ATP + AMP

Or AMP may be produced by the hydrolysis of one high energy phosphate bond of ADP:

ADP → AMP + P_i

AMP can also be formed by hydrolysis of ATP into AMP and pyrophosphate:

ATP → AMP + PP_i

When RNA is broken down by living systems, nucleoside monophosphates, including adenosine monophosphate, are formed.

AMP can be regenerated to ATP as follows:

AMP + ATP → 2 ADP (adenylate kinase in the opposite direction)

ADP + P_i → ATP (this step is most often performed in aerobes by the ATP synthase during oxidative phosphorylation)

AMP can be converted into IMP by the enzyme myoadenylate deaminase, freeing an ammonia group.

In a catabolic pathway, adenosine monophosphate can be converted to uric acid, which is excreted from the body.

cAMP

AMP can also exist as a cyclic structure known as cyclic AMP (or cAMP). Within certain cells the enzyme adenylate cyclase makes cAMP from ATP, and typically this reaction is regulated by hormones such as adrenaline or glucagon. cAMP plays an important role in intracellular signaling.

See also

• DNA
• Oligonucleotide
• Phosphodiesterase

References

External links

• GMD MS Spectrum
• require('Module:No globals')

local function getCatForId( id )

   local title = mw.title.getCurrentTitle()
   local namespace = title.namespace
   if namespace == 0 then

return ''

   elseif namespace == 2 and not title.isSubpage then

return ''

   else

return ''

   end

end

local function viafLink( id )

   if not string.match( id, '^%d+$' ) then
       return false
   end
   return '.. id .. ' ' .. id .. '' .. getCatForId( 'VIAF' )

end

local function kulturnavLink( id )

   return '.. id .. ' id' 

end

local function sikartLink( id )

   return '.. id .. '&lng=en ' .. id .. '' 

end

local function tlsLink( id ) local id2 = mw.ustring.gsub(id, '%s', function(s) return mw.uri.encode(s, 'WIKI') end)

   return '.. id2 .. ' ' .. id .. '' 

end

local function ciniiLink( id )

   return '.. id .. '?l=en ' .. id .. '' 

end

local function bneLink( id )

   return '.. id .. ' ' .. id .. '' 

end

local function uscongressLink( id )

   return '.. id .. ' ' .. id .. '' 

end

local function narapersonLink( id )

   return '.. id .. ' ' .. id .. '' 

end

local function naraorganizationLink( id )

   return '.. id .. ' ' .. id .. '' 

end

local function botanistLink( id ) local id2 = mw.ustring.gsub(id, '%s', function(s) return mw.uri.encode(s, 'PATH') end)

   return '.. id2 .. ' ' .. id .. '' 

end

local function mgpLink( id )

   -- TODO Implement some sanity checking regex
   return '.. id .. ' ' .. id .. '' 

end

local function rslLink( id )

   -- TODO Implement some sanity checking regex
   return '.. id .. '&CON_LNG=ENG ' .. id .. ''

end

local function leonoreLink( id ) -- Identifiants allant de LH/1/1 à LH/2794/54 (légionnaires) -- Identifiants allant de C/0/1 à C/0/84 (84 légionnaires célèbres) -- Identifiants allant de 19800035/1/1 à 19800035/385/51670 (légionnaires décédés entre 1954 et 1977, et quelques dossiers de légionnaires décédés avant 1954)

   if not string.match( id, '^LH/%d%d?%d?%d?/%d%d?%d?$' ) and
      not string.match( id, '^C/0/%d%d?$' ) and
           not string.match( id, '^19800035/%d%d?%d?%d?/%d%d?%d?%d?%d?$' ) then
       return false
   end
   return '.. id .. ' ' .. id .. '' 

end

local function sbnLink( id )

   if not string.match( id, '^IT\\ICCU\\%d%d%d%d%d%d%d%d%d%d$' ) and not string.match( id, '^IT\\ICCU\\%u%u[%d%u]%u\\%d%d%d%d%d%d$' ) then
       return false
   end
   return '.. id .. ' ' .. id .. '' .. getCatForId( 'SBN' )

end

local function nkcLink( id ) return '.. id .. '&CON_LNG=ENG ' .. id .. '' end

local function nclLink( id )

   if not string.match( id, '^%d+$' ) then
       return false
   end
   return '.. id .. '&CON_LNG=ENG ' .. id .. '' 

end

local function ndlLink( id ) return '.. id .. ' ' .. id .. '' end

local function sudocLink( id )

   if not string.match( id, '^%d%d%d%d%d%d%d%d[%dxX]$' ) then
       return false
   end
   return '.. id .. ' ' .. id .. '' 

end

local function hlsLink( id )

   if not string.match( id, '^%d+$' ) then
       return false
   end
   return '.. id .. '.php ' .. id .. ''

end

local function lirLink( id )

   if not string.match( id, '^%d+$' ) then
       return false
   end
   return '.. id .. '.450.0.html ' .. id .. ''

end

local function splitLccn( id )

   if id:match( '^%l%l?%l?%d%d%d%d%d%d%d%d%d?%d?$' ) then
       id = id:gsub( '^(%l+)(%d+)(%d%d%d%d%d%d)$', '%1/%2/%3' )
   end
   if id:match( '^%l%l?%l?/%d%d%d?%d?/%d+$' ) then
        return mw.text.split( id, '/' )
   end
   return false

end

local function append(str, c, length)

   while str:len() < length do
       str = c .. str
   end
   return str

end

local function lccnLink( id )

   local parts = splitLccn( id )
   if not parts then
       return false
   end
   local lccnType = parts[1] ~= 'sh' and 'names' or 'subjects'
   id = parts[1] .. parts[2] .. append( parts[3], '0', 6 )
   return '.. lccnType .. '/' .. id .. ' ' .. id .. '' .. getCatForId( 'LCCN' )

end

local function mbLink( id )

   -- TODO Implement some sanity checking regex
   return '.. id .. ' ' .. id .. '' .. getCatForId( 'MusicBrainz' )

end

--Returns the ISNI check digit isni must be a string where the 15 first elements are digits local function getIsniCheckDigit( isni )

   local total = 0
   for i = 1, 15 do
       local digit = isni:byte( i ) - 48 --Get integer value
       total = (total + digit) * 2
   end
   local remainder = total % 11
   local result = (12 - remainder) % 11
   if result == 10 then
       return "X"
   end
   return tostring( result )

end

--Validate ISNI (and ORCID) and retuns it as a 16 characters string or returns false if it's invalid --See http://support.orcid.org/knowledgebase/articles/116780-structure-of-the-orcid-identifier local function validateIsni( id )

   id = id:gsub( '[ %-]', ):upper()
   if not id:match( '^%d%d%d%d%d%d%d%d%d%d%d%d%d%d%d[%dX]$' ) then
       return false
   end
   if getIsniCheckDigit( id ) ~= string.char( id:byte( 16 ) ) then
       return false
   end
   return id

end

local function isniLink( id )

   id = validateIsni( id )
   if not id then
       return false
   end
   return '.. id .. ' ' .. id:sub( 1, 4 ) .. ' ' .. id:sub( 5, 8 ) .. ' '  .. id:sub( 9, 12 ) .. ' '  .. id:sub( 13, 16 ) .. '' .. getCatForId( 'ISNI' )

end

local function orcidLink( id )

   id = validateIsni( id )
   if not id then
       return false
   end
   id = id:sub( 1, 4 ) .. '-' .. id:sub( 5, 8 ) .. '-'  .. id:sub( 9, 12 ) .. '-'  .. id:sub( 13, 16 )
   return '.. id .. ' ' .. id .. '' .. getCatForId( 'ORCID' )

end

local function gndLink( id )

   return '.. id .. ' ' .. id .. '' .. getCatForId( 'GND' )

end

local function selibrLink( id ) if not string.match( id, '^%d+$' ) then

       return false
   end
   return '.. id .. ' ' .. id .. '' .. getCatForId( 'SELIBR' )

end

local function bnfLink( id )

   --Add cb prefix if it has been removed
   if not string.match( id, '^cb.+$' ) then
       id = 'cb' .. id
   end

   return '.. id .. ' ' .. id .. ' .. id .. ' (data)' .. getCatForId( 'BNF' )

end

local function bpnLink( id )

   if not string.match( id, '^%d+$' ) then
       return false
   end
   return '.. id .. ' ' .. id .. '' .. getCatForId( 'BPN' )

end

local function ridLink( id )

   return '.. id .. ' ' .. id .. '' .. getCatForId( 'RID' )

end

local function bibsysLink( id )

   return '.. id .. '&feltselect=bs.autid ' .. id .. '' .. getCatForId( 'BIBSYS' )

end

local function ulanLink( id )

   return '.. id .. ' ' .. id .. '' .. getCatForId( 'ULAN' )

end

local function nlaLink( id ) return '.. id .. ' ' .. id .. '' .. getCatForId( 'NLA' ) end

local function rkdartistsLink( id ) return '.. id .. ' ' .. id .. '' .. getCatForId( 'RKDartists' ) end

local function getIdsFromWikidata( item, property )

   local ids = {}
   if not item.claims[property] then
       return ids
   end
   for _, statement in pairs( item.claims[property] ) do
         if statement.mainsnak.datavalue then
          table.insert( ids, statement.mainsnak.datavalue.value )
         end
   end
   return ids

end

local function matchesWikidataRequirements( item, reqs )

   for _, group in pairs( reqs ) do
       local property = 'p' .. group[1]
       local qid = group[2]
       if item.claims[property] ~= nil then
           for _, statement in pairs ( item.claims[property] ) do
                if statement.mainsnak.datavalue ~= nil then
                        if statement.mainsnak.datavalue.value['numeric-id'] == qid then
                        return true
                end
            end
           end
       end
   end
   return false

end

local function createRow( id, label, rawValue, link, withUid )

   if link then
       if withUid then
           return '* ' .. label .. ' ' .. link .. '\n'
       else
           return '* ' .. label .. ' ' .. link .. '\n'
       end
   else

return '* \n'

   end

end

--In this order: name of the parameter, label, propertyId in Wikidata, formatting function local conf = {

   { 'VIAF', 'VIAF', 214, viafLink },
   { 'LCCN', 'LCCN', 244, lccnLink },
   { 'ISNI', 'ISNI', 213, isniLink },
   { 'ORCID', 'ORCID', 496, orcidLink },
   { 'GND', 'GND', 227, gndLink },
   { 'SELIBR', 'SELIBR', 906, selibrLink },
   { 'SUDOC', 'SUDOC', 269, sudocLink },    
   { 'BNF', 'BNF', 268, bnfLink },
   { 'BPN', 'BPN', 651, bpnLink },
   { 'RID', 'ResearcherID', 1053, ridLink },
   { 'BIBSYS', 'BIBSYS', 1015, bibsysLink },
   { 'ULAN', 'ULAN', 245, ulanLink },
   { 'HDS', 'HDS', 902, hlsLink },
   { 'LIR', 'LIR', 886, lirLink },
   { 'MBA', 'MusicBrainz', 434, mbLink },
   { 'MGP', 'MGP', 549, mgpLink },    
   { 'NLA', 'NLA', 409, nlaLink },
   { 'NDL', 'NDL', 349, ndlLink },
   { 'NCL', 'NCL', 1048, nclLink },
   { 'NKC', 'NKC', 691, nkcLink },
   { 'Léonore', 'Léonore', 640, leonoreLink }, 
   { 'SBN', 'ICCU', 396, sbnLink },     
   { 'RLS', 'RLS', 947, rslLink },
   { 'Botanist', '[[Author ci