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Androstadienone

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Title: Androstadienone  
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Subject: Fear, Mammalian pheromones, Hyperosmia, Steroid hormones, Gender dysphoria
Collection: Human Pheromones, Mammalian Pheromones, Neurosteroids, Steroids
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Androstadienone

Androstadienone
Systematic (IUPAC) name
(8S,9S,10R,13R,14S)-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15-decahydrocyclopenta[a]phenanthren-3-one
Clinical data
Legal status
?
Identifiers
CAS number  YesY
ATC code None
PubChem
ChemSpider  YesY
Chemical data
Formula C19H26O 
Mol. mass 270.408 g/mol
 YesY   

Androstadienone, also known as androsta-4,16,-dien-3-one, is a chemical compound that has been described as having strong pheromone-like activities in humans.[1] It is a metabolite of the sex hormone testosterone: however, androstadienone does not exhibit any known androgenic or anabolic effects. Though it has been reported to significantly affect the mood of heterosexual women and homosexual men, it does not alter behavior overtly,[2] although it may have more subtle effects on attention.[3] Androstadienone is commonly sold in male fragrances, it is purported, to increase sexual attraction.

See also

References

  1. ^ Wyart C, Webster WW, Chen JH, Wilson SR, McClary A, Khan RM, Sobel N (February 2007). "Smelling a single component of male sweat alters levels of cortisol in women".  
  2. ^ Lundström JN, Olsson MJ (December 2005). "Subthreshold amounts of social odorant affect mood, but not behavior, in heterosexual women when tested by a male, but not a female, experimenter". Biol Psychol 70 (3): 197–204.  
  3. ^ Hummer TA, McClintock MK (April 2009). "Putative human pheromone androstadienone attunes the mind specifically to emotional information". Horm Behav 55 (4): 548–59.  

External links

  • A critical review of the evidence for the existence (1) human pheromones and (2) a functional vomeronasal organ (VNO) in humans
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