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Title: Budipine  
Author: World Heritage Encyclopedia
Language: English
Subject: Safinamide, Midafotel, Tiletamine, Glycine, Antiparkinson
Collection: Antiparkinsonian Agents, Piperidines
Publisher: World Heritage Encyclopedia


Systematic (IUPAC) name
Clinical data
Legal status
CAS number  YesY
ATC code N04
ChemSpider  YesY
Chemical data
Formula C21H27N 
Mol. mass 293.446 g/mol

Budipine is an antiparkinson agent.

Its mechanism of action is not well characterized.[2] It is believed to be an NMDA receptor antagonist,[3] however, promoting the synthesis of dopamine.[4]

Because it provides additional benefits relative to existing treatments, it probably does not precisely mimic the mechanism of an existing known treatment.[5]

See also


  1. ^ Martndale: The Complete Drug Reference, 35th Ed.
  2. ^ Reichmann H (October 2006). "Budipine in Parkinson's tremor". J. Neurol. Sci. 248 (1-2): 53–5.  
  3. ^ J. Kornhuber, B. Herr, J. Thome, P. Riederer. "The antiparkinsonian drug budipine binds to NMDA and sigma receptors in postmortem human brain tissue". J.Neural Transm.Suppl. 46:127-133, 1995. PMID 8821048
  4. ^ "". 
  5. ^ Przuntek H, Bittkau S, Bliesath H, et al. (May 2002). "Budipine provides additional benefit in patients with Parkinson disease receiving a stable optimum dopaminergic drug regimen". Arch. Neurol. 59 (5): 803–6.  

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