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C5a receptor

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C5a receptor

Complement component 5a receptor 1
Identifiers
Symbols  ; C5A; C5AR; C5R1; CD88
External IDs IUPHAR: ChEMBL: GeneCards:
RNA expression pattern
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)
RefSeq (protein)
Location (UCSC)
PubMed search

The C5a receptor also known as complement component 5a receptor 1 (C5AR1) or CD88 (Cluster of Differentiation 88) is a G protein-coupled receptor for C5a. It functions as a complement receptor.[1]

C5a receptor structure and its residues possessing role in ligand binding or signaling.

Cells

The C5a receptor is expressed on:[2]

See also

References

  1. ^ Gerard C, Gerard NP (1994). "C5A anaphylatoxin and its seven transmembrane-segment receptor". Annu. Rev. Immunol. 12: 775–808.  
  2. ^ Klos A, Wende E, Wareham KJ, Monk PN. (2013). "International Union of Pharmacology. LXXXVII. Complement peptide C5a, C4a, and C3a receptors". Pharmacol. Rev. 65 (1): 500–43.  

Further reading

External links


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