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Title: Cul7  
Author: World Heritage Encyclopedia
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Subject: Postreplication checkpoint, Cellular apoptosis susceptibility protein, CDKN2D, Cyclin B2, CDKN2C
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Cullin 7
PDB rendering based on 2jng.
Available structures
PDB Ortholog search: PDBe, RCSB
Symbols  ; 3M1; KIAA0076; dJ20C7.5
External IDs GeneCards:
RNA expression pattern
Species Human Mouse
RefSeq (mRNA)
RefSeq (protein)
Location (UCSC)
PubMed search

Cullin-7 is a RING-E3 ligase protein that in humans is encoded by the CUL7 gene.[1][2][3]

Clinical significance

It is associated with 3-M syndrome.


CUL7 has been shown to interact with RBX1.[1]


  1. ^ a b
  2. ^
  3. ^

Further reading

External links

  • GeneReviews/NIH/NCBI/UW entry on 3-M syndrome
  • OMIM entries entry on 3-M syndrome

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