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Title: Chlorotrianisene  
Author: World Heritage Encyclopedia
Language: English
Subject: Conjugated estrogen, Estrone sulfate, Formestane, Estradiol acetate, Mestranol
Collection: Organochlorides, Phenol Ethers, Synthetic Estrogens
Publisher: World Heritage Encyclopedia


Systematic (IUPAC) name
1,1',1''-(2-chloroethene-1,1,2-triyl)tris(4-methoxybenzene); 11-chloro-4,13-dimethoxy-12-(p-methoxyphenyl)stilbene
Clinical data
Trade names Tace
  • US: X (Contraindicated)
Legal status
  • Discontinued
Routes of
Pharmacokinetic data
Protein binding 50 to 80%
CAS Registry Number  Y
ATC code G03
PubChem CID:
DrugBank  Y
ChemSpider  Y
Chemical data
Formula C23H21ClO3
Molecular mass 380.864 g/mol

Chlorotrianisene (trade name Tace) is a non-steroidal synthetic estrogen that was formerly used for the treatment of menopause, deficiencies in ovary function, and prostate cancer.[1][2]


  1. ^ Chlorotrianisene
  2. ^ Yuen, B. H.; Pendleton, H. J.; Blair, S. (1977). "Efficacy of bromocriptine and chlorotrianisene in preventing postpartum lactation". Canadian Medical Association journal 117 (8): 919–921.  

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