Chlorproethazine

Chlorproethazine

IUPAC name 3-(2-chlorophenothiazin-10-yl)-N,N-diethylpropan-1-amine
Identifiers
CAS number	4611-02-3
PubChem	65750
ChemSpider	59173
KEGG	D07308 ^Y
ATC code	AA07
Jmol-3D images	Image 1
SMILES Clc2cc1N(c3c(Sc1cc2)cccc3)CCCN(CC)CC
InChI InChI=1S/C19H23ClN2S/c1-3-21(4-2)12-7-13-22-16-8-5-6-9-18(16)23-19-11-10-15(20)14-17(19)22/h5-6,8-11,14H,3-4,7,12-13H2,1-2H3 Key: DBOUGBAQLIXZLV-UHFFFAOYSA-N InChI=1/C19H23ClN2S/c1-3-21(4-2)12-7-13-22-16-8-5-6-9-18(16)23-19-11-10-15(20)14-17(19)22/h5-6,8-11,14H,3-4,7,12-13H2,1-2H3 Key: DBOUGBAQLIXZLV-UHFFFAOYAP
Properties
Molecular formula	C₁₉H₂₃ClN₂S
Molar mass	346.91732 g/mol
Y (verify) (what is: Y/N?) Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Chlorproethazine is an antipsychotic.

Synthesis

Chlorproethazine can be synthesized from a diphenylsulfide derivative.^[1]

References

Antipsychotics (neuroleptics) (N05A)

Typical

Benzamides: Levosulpiride; Nemonapride; Sulpiride; Sultopride; Tiapride; Veralipride

Butyrophenones: Azaperone; Benperidol; Bromperidol; Droperidol; Fluanisone; Haloperidol; Lenperone; Moperone; Pipamperone; Spiperone; Timiperone; Trifluperidol

Diphenylbutylpiperidines: Clopimozide; Fluspirilene; Penfluridol; Pimozide

Phenothiazines: Acepromazine; Acetophenazine; Butaperazine; Carphenazine; Chloracizine; Chlorproethazine; Chlorpromazine; Cyamemazine; Dixyrazine; Fluacizine; Fluphenazine; Levomepromazine/Methotrimeprazine; Mesoridazine; Perazine; Pericyazine; Perphenazine; Piperacetazine; Pipotiazine; Prochlorperazine; Promazine; Promethazine; Propiomazine; Sulforidazine; Thiethylperazine; Thiopropazate; Thioproperazine; Thioridazine; Trifluoperazine; Triflupromazine

Thioxanthenes: Chlorprothixene; Clopenthixol; Flupentixol; Thiothixene; Zuclopenthixol

Tricyclics: Butaclamol; Fluotracen; Loxapine; Trimipramine

Others: Prothipendyl

Atypical

Benzamides: Amisulpride; Remoxipride‡

Butyrophenones: Cinuperone; Melperone; Setoperone

Benzo(iso)oxazole piperidines: Iloperidone; Ocaperidone; Paliperidone; Risperidone

Benzo(iso)thiazole piperazines: Lurasidone; Perospirone; Revospirone; Tiospirone; Ziprasidone

Diphenylbutylpiperazines: Amperozide

Phenylpiperazines: Aripiprazole; Bifeprunox; Brexpiprazole^†; Elopiprazole; Umespirone

Tricyclics: Amoxapine; Asenapine; Carpipramine; Clocapramine; Clorotepine; Clotiapine; Clozapine; Fluperlapine; Gevotroline; Metitepine; Mosapramine; NDMC; Olanzapine; Piquindone; Quetiapine; Tenilapine; Zotepine

Others: Blonanserin; Cariprazine; Molindone; Pimavanserin; Roxindole; Sarizotan; Sertindole; Spiramide; Zicronapine^†

Others

^#WHO-EM
^‡Withdrawn from market
Clinical trials:
- ^†Phase III
- ^§Never to phase III

M: PSO/PSI

mepr

dsrd (o, p, m, p, a, d, s), sysi/epon, spvo

proc (eval/thrp), drug (N5A/5B/5C/6A/6B/6D)

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Chlorproethazine