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Title: Cyclorphan  
Author: World Heritage Encyclopedia
Language: English
Subject: List of opioids, Phenols, Kobret, 6β-Naltrexol-d4, Hemorphin
Collection: Morphinans, Phenols, Psychedelics, Dissociatives and Deliriants, Synthetic Opioids
Publisher: World Heritage Encyclopedia


Systematic (IUPAC) name
Clinical data
Legal status
CAS number
ATC code ?
Chemical data
Formula C20H27NO 
Mol. mass 297.434 g/mol

Cyclorphan is a hallucinogenic opioid mixed agonist–antagonist related to levorphanol discovered in the late 1960s. It is not marketed as an analgesic because of side effects related to its impact on the kappa opioid receptor,[1][2] but has found some use as a research chemical on and off since its discovery.


  1. ^ Herling, S, Hein, DW, Nemeth, MA, Valentino, RJ, Woods, JH. (Jan 1982). "Discriminative stimulus, antagonist, and rate-decreasing effects of cyclorphan: multiple modes of action". Life Sciences 30 (4): 331–41.  
  2. ^ Bertalmio, AJ, Woods, JH. (1992). "Discriminative stimulus effects of cyclorphan: selective antagonism with naltrexone". Psychopharmacology (Berlin) 106 (2): 189–94.  

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