World Library  
Flag as Inappropriate
Email this Article

Far East scarlet-like fever

Article Id: WHEBN0037897076
Reproduction Date:

Title: Far East scarlet-like fever  
Author: World Heritage Encyclopedia
Language: English
Subject: Scarlet fever, Rickettsia africae, Rickettsia honei, Rickettsia japonica, Helicobacter cellulitis
Collection: Bacterial Diseases, Scarlet Fever
Publisher: World Heritage Encyclopedia
Publication
Date:
 

Far East scarlet-like fever

Far East scarlet-like fever or scarlatinoid fever is an infectious disease caused by the gram negative bacillus Yersinia pseudotuberculosis. In Japan it is called Izumi fever.[1]

Contents

  • History 1
  • Etiology 2
  • Pathophysiology 3
  • Clinical features 4
    • Diferential diagnosis 4.1
  • References 5

History

The first outbreak of this disease was reported from the Pacific coastal areas (Primorsky Krai) of Russia in the 1950s.

Etiology

The cause of this disease is Yersinia pseudotuberculosis serotype O1. 95% are subtype O1b.

Yersinia pseudotuberculosis has been divided into 6 genetic groups: group 1 has only been isolated from the Far East.[2]

Pathophysiology

The clinical features of this disease appear to be due—at least in part—to the production of a superantigen—YpM (yersina pseudotuberculosis-derived mitogen). This is present in almost all strains from the Far East but only 20% of European isolates.[3] The antigen was discovered in 1993 and is encoded by a 456 base gene. The protein has 151 amino acids with a signal sequence of 20 amino acids. The mitogenic antigens are scattered across the protein but two cysteine residues (residues 32 and 129) which form a disulphide bridge are critical.

The bacteriophage given the nearby presence of a phage integration site but the mechanism of entry into the genome is not currently known.

Clinical features

These include[4][5]

  • erythematous skin rash usually of the face, elbows and knees
  • skin desquamation
  • exanthema
  • hyperaemic tongue
  • toxic shock syndrome

Other features include mesenteric lymphadenitis and arthritis. Renal failure while rare may occur.

Relapses occur in up to 50% of patients.

Diferential diagnosis

The main differential diagnosis is scarlet fever.[6]

References

  1. ^ Sato K, Ouchi K, Taki M (1983) Yersinia pseudotuberculosis infection in children, resembling Izumi fever and Kawasaki syndrome. Pediatr Infect Dis 2: 123–126
  2. ^ Fukushima H Matsuda Y, Seki R, Tsubokura M, Takeda N, Shubin FN, Paik IK, Zheng XB (2001) Geographical heterogeneity between Far Eastern and Western countries in prevalence of the virulence plasmid, the superantigen Yersinia pseudotuberculosis-derived mitogen, and the high-pathogenicity island among Yersinia pseudotuberculosis strains. J Clin Microbiol 39:3541–3547
  3. ^ a b Yoshino K, Ramamurthy T, Nair GB, Fukushima H, Ohtomo Y, Takeda N, Kaneko S, Takeda T (1995) Geographical heterogeneity between Far East and Europe in prevalence of ypm gene encoding the novel superantigen among Yersinia pseudotuberculosis strains. J Clin Microbiol 33(12) 3356–3358
  4. ^ Zalmover IIu, Znamenskiĭ VA, Ignatovich VO, Vishniakov AK, Serov GD (1969) Clinical aspects of Far Eastern scarlatina-like fever. Voen Med Zh 1:47–51
  5. ^ Solozhenkin VG (1978) Scarlet fever-like disease in children. Pediatriia (1):27–28
  6. ^ Antonov VS (1978) Differential diagnosis of scarlet fever-like forms of pseudotuberculosis and scarlet fever in children. Pediatriia 52(1):6–9
This article was sourced from Creative Commons Attribution-ShareAlike License; additional terms may apply. World Heritage Encyclopedia content is assembled from numerous content providers, Open Access Publishing, and in compliance with The Fair Access to Science and Technology Research Act (FASTR), Wikimedia Foundation, Inc., Public Library of Science, The Encyclopedia of Life, Open Book Publishers (OBP), PubMed, U.S. National Library of Medicine, National Center for Biotechnology Information, U.S. National Library of Medicine, National Institutes of Health (NIH), U.S. Department of Health & Human Services, and USA.gov, which sources content from all federal, state, local, tribal, and territorial government publication portals (.gov, .mil, .edu). Funding for USA.gov and content contributors is made possible from the U.S. Congress, E-Government Act of 2002.
 
Crowd sourced content that is contributed to World Heritage Encyclopedia is peer reviewed and edited by our editorial staff to ensure quality scholarly research articles.
 
By using this site, you agree to the Terms of Use and Privacy Policy. World Heritage Encyclopedia™ is a registered trademark of the World Public Library Association, a non-profit organization.
 


Copyright © World Library Foundation. All rights reserved. eBooks from Project Gutenberg are sponsored by the World Library Foundation,
a 501c(4) Member's Support Non-Profit Organization, and is NOT affiliated with any governmental agency or department.