World Library  
Flag as Inappropriate
Email this Article


Article Id: WHEBN0004336497
Reproduction Date:

Title: Flurbiprofen  
Author: World Heritage Encyclopedia
Language: English
Subject: Felbinac, Ketoprofen, Aspirin, Propacetamol, Morazone
Collection: Non-Steroidal Anti-Inflammatory Drugs, Organofluorides, Phenyl Alkanoic Acids
Publisher: World Heritage Encyclopedia


Systematic (IUPAC) name
(RS)-2-(2-fluorobiphenyl-4-yl)propanoic acid
Clinical data
Trade names Ansaid, Ocufen, Strepfen
Pregnancy cat.
Legal status
  • POM
Routes Oral
Pharmacokinetic data
Protein binding > 99%
Metabolism Hepatic (CYP2C9)
Half-life 4.7-5.7 hours
Excretion Renal
CAS number  YesY
ATC code M01 , M02, R02, S01
IUPHAR ligand
ChemSpider  YesY
Synonyms (±)-2-fluoro-α-methyl-(1,1'-biphenyl)-4-acetic acid
PDB ligand ID FLP (, )
Chemical data
Formula C15H13FO2 
Mol. mass 244.261 g/mol
Physical data
Melt. point 117 °C (243 °F)

Flurbiprofen is a member of the phenylalkanoic acid derivative family of non-steroidal anti-inflammatory drugs (NSAIDs) used to treat the inflammation and pain of arthritis.[1] It is known as "Ansaid" marketed by Pfizer and "Froben" by Abbott.

Flurbiprofen is also used as an active ingredient in some kinds of throat lozenges (Strepsils Intensive).

A single enantiomer of flurbiprofen, tarenflurbil [(R)-flurbiprofen)], is currently in clinical trials for the treatment of metastatic prostate cancer.


  1. ^ "Medical Dictionary, Houghton Mifflin Company". Retrieved July 21, 2010. 

This article was sourced from Creative Commons Attribution-ShareAlike License; additional terms may apply. World Heritage Encyclopedia content is assembled from numerous content providers, Open Access Publishing, and in compliance with The Fair Access to Science and Technology Research Act (FASTR), Wikimedia Foundation, Inc., Public Library of Science, The Encyclopedia of Life, Open Book Publishers (OBP), PubMed, U.S. National Library of Medicine, National Center for Biotechnology Information, U.S. National Library of Medicine, National Institutes of Health (NIH), U.S. Department of Health & Human Services, and, which sources content from all federal, state, local, tribal, and territorial government publication portals (.gov, .mil, .edu). Funding for and content contributors is made possible from the U.S. Congress, E-Government Act of 2002.
Crowd sourced content that is contributed to World Heritage Encyclopedia is peer reviewed and edited by our editorial staff to ensure quality scholarly research articles.
By using this site, you agree to the Terms of Use and Privacy Policy. World Heritage Encyclopedia™ is a registered trademark of the World Public Library Association, a non-profit organization.

Copyright © World Library Foundation. All rights reserved. eBooks from Project Gutenberg are sponsored by the World Library Foundation,
a 501c(4) Member's Support Non-Profit Organization, and is NOT affiliated with any governmental agency or department.