Galactosyltransferase

Galactosyltransferase
Identifiers
Symbol Galactosyl_T
Pfam InterPro IPR002659


Galactosyltransferase is a type of glycosyltransferase which catalyzes the transfer of galactose. An example is B-N-acetylglucosaminyl-glycopeptide b-1,4-galactosyltransferase.

The biosynthesis of disaccharides, oligosaccharides and polysaccharides involves the action of hundreds of different glycosyltransferases. These enzymes catalyse the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. A classification of glycosyltransferases using nucleotide diphospho-sugar, nucleotide monophospho-sugar and sugar phosphates ( The same three-dimensional fold is expected to occur within each of the families. Because 3-D structures are better conserved than sequences, several of the families defined on the basis of sequence similarities may have similar 3-D structures and therefore form 'clans'.

Glycosyltransferase family 31 (

Human galactosyltransferases

B3GALNT1; B3GALNT2; B3GALT1; B3GALT2; B3GALT4; B3GALT5; B3GALT6; B3GNT2; B3GNT3; B3GNT4; B3GNT5; B3GNT6; B3GNT7; B3GNT8;

B4GALNT1; B4GALNT2; B4GALNT3; B4GALNT4;

B4GALT1; B4GALT2; B4GALT3; B4GALT4; B4GALT5; B4GALT6; B4GALT7;

GALNT1; GALNT2; GALNT3; GALNT4; GALNT5; GALNT6; GALNT7; GALNT8; GALNT9; GALNT10; GALNT11; GALNT12; GALNT13; GALNT14;

GALNTL1; GALNTL2; GALNTL4; GALNTL5; GALNTL6;

References

External links

  • Medical Subject Headings (MeSH)

This article incorporates text from the IPR002659


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