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Kallidin

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Title: Kallidin  
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Subject: Bradykinin receptor, Kinin, Bradykinin, List of MeSH codes (D12.644), Low-molecular-weight kininogen
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Kallidin

Kallidin
Names
IUPAC name
L-lysyl-L-arginyl-L-prolyl-L-prolyl-glycyl-L-phenylalanyl-L-seryl-L-prolyl-L-phenylalanyl-L-arginine
Identifiers
 Y
ChemSpider  Y
Jmol-3D images Image
MeSH
PubChem
Properties
C56H85N17O12
Molar mass 1188.38 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
 Y  (: Y/N?)

Kallidin is a bioactive kinin formed in response to injury from kininogen precursors through the action of kallikreins.

Kallidin is a decapeptide whose sequence is H-Lys-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-OH. It can be converted to bradykinin by the aminopeptidase enzyme.

It can be a substrate for carboxypeptidase M and N.[1]

Kallidin is identical to bradykinin with an additional lysine residue added at the N-terminal end and signals through the bradykinin receptor.

References

  1. ^ Stefan Offermanns; Walter Rosenthal (2008). Encyclopedia of Molecular Pharmacology. Springer. pp. 673–.  
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