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Lu AE58054

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Title: Lu AE58054  
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Subject: Lundbeck, 5-HT6 receptor
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Lu AE58054

Lu AE58054
Systematic (IUPAC) name
Clinical data
Legal status
CAS number  N
ATC code None
ChemSpider  N
Synonyms Lu-AE-58054
Chemical data
Formula C20H19F5N2O 
Mol. mass 398.37 g/mol

Lu AE58054 is a potent and selective 5-HT6 receptor antagonist under development by Lundbeck as an augmentation therapy for the treatment of cognitive deficits associated with Alzheimer's disease and schizophrenia.[1][2] As of October 2013 it is in phase III clinical trials.[2]


  1. ^ "U.S. Development Programs. - Lundbeck". 
  2. ^ a b "Search of: Lu AE58054 - List Results -". 

External links

  • Lundbeck expands its pipeline - initiating phase II clinical trials with a new compound for the treatment of schizophrenia
  • Lundbeck initiates clinical phase II trials with Lu AE58054 as augmentation treatment in Alzheimer's disease

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