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Title: Olsalazine  
Author: World Heritage Encyclopedia
Language: English
Subject: Gastroenterology, Paregoric, Thiorphan, Balsalazide, Racecadotril
Publisher: World Heritage Encyclopedia


Olsalazine is an anti-inflammatory drug used in the treatment of inflammatory bowel disease such as ulcerative colitis. It is sold under the name Dipentum.

The chemical name is 3,3' -azobis (6-hydroxybenzoate)salicylic acid. It is sold as the disodium salt.

Like balsalazide, olsalazine is believed to deliver mesalazine, or 5-aminosalicylic acid (5-ASA), past the small intestine, directly to the large intestine, which is the active site of disease in ulcerative colitis.


  • History 1
  • Supply 2
  • Other indications 3
  • External links 4


Olsalazine gained Food and Drug Administration (FDA) approval in 1990.


The drug is supplied by UCB Pharma.

Other indications

The Australian biotech company Giaconda has developed a combination therapy for treating constipation-predominant irritable bowel syndrome that uses olsalazine and the anti-gout drug colchicine.

External links

  • Olsalazine official site
  • Medicine Net

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