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Pituitary disease

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Title: Pituitary disease  
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Subject: Goitre, Adrenocorticotropic hormone, Hypothyroidism, Pituitary tumour, Pituitary adenoma, Hypophysitis
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Pituitary disease

Pituitary disease
Classification and external resources
MeSH D010900

A Pituitary disease is a disorder primarily affecting the pituitary gland.[1]

The main disorders involving the pituitary gland are:

Condition Direction Hormone
Acromegaly overproduction growth hormone
Cushing's disease overproduction Adrenocorticotropic hormone
Growth hormone deficiency underproduction growth hormone
Syndrome of inappropriate antidiuretic hormone overproduction vasopressin
Diabetes insipidus
(can also be nephrogenic)
underproduction vasopressin
Sheehan syndrome underproduction any pituitary hormone
Pickardt-Fahlbusch-Syndrome underproduction any pituitary hormone, except prolactin, which is increased
Hyperpituitarism (most commonly pituitary adenoma) overproduction any pituitary hormone
Hypopituitarism underproduction any pituitary hormone

Over- or underproduction of a pituitary hormone will effect the respective end-organ. For example insufficient production (hyposecretion) of thyroid stimulating hormone (TSH) in the pituitary gland will cause hypothyroidism, while overproduction (hypersecretion) of TSH will cause hyperthyroidism. Thyroidisms caused by the pituitary gland are less common though, accounting for less than 10% of all hypothyroidism cases and much less than 1% of hyperthyroidism cases.[2][3]

See also


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