World Library  
Flag as Inappropriate
Email this Article

Stenbolone

Article Id: WHEBN0023951510
Reproduction Date:

Title: Stenbolone  
Author: World Heritage Encyclopedia
Language: English
Subject: Anabolic steroid, Epitiostanol, Bolazine, Hydroxystenozole, Mebolazine
Collection:
Publisher: World Heritage Encyclopedia
Publication
Date:
 

Stenbolone

Stenbolone
Identifiers
CAS number  YesY
PubChem
Jmol-3D images Image 1
Properties
Molecular formula C20H30O2
Molar mass 302.45 g/mol
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
 YesY   YesY/N?)

Stenbolone is an anabolic steroid. It is structurally similar to 1-testosterone.

Synthesis

The route used to prepare the unsaturated 2 methyl androgen stenbolone provides yet a further illustration of the propensity for the formation of enolates at the 2 position.[1]

Preparation of the acetate ester of stenbolone

Thus reaction of dihydrotestosterone acetate with formaldehyde and dimethylamine gives the Mannich product. Hydrogenolysis of that product gives the 2-methyl derivative via elimination of dimethylamine. Bromination of the ketone leads to the 2-bromo derivative. Dehydrobromination by means of lithium carbonate in dimethyl formamide (DMF) affords the androgen stenbolone acetate.

References

  1. ^ U.S. Patent 3,361,773 Wiechert Rudolf; (1968). Schering AG, Berlin


This article was sourced from Creative Commons Attribution-ShareAlike License; additional terms may apply. World Heritage Encyclopedia content is assembled from numerous content providers, Open Access Publishing, and in compliance with The Fair Access to Science and Technology Research Act (FASTR), Wikimedia Foundation, Inc., Public Library of Science, The Encyclopedia of Life, Open Book Publishers (OBP), PubMed, U.S. National Library of Medicine, National Center for Biotechnology Information, U.S. National Library of Medicine, National Institutes of Health (NIH), U.S. Department of Health & Human Services, and USA.gov, which sources content from all federal, state, local, tribal, and territorial government publication portals (.gov, .mil, .edu). Funding for USA.gov and content contributors is made possible from the U.S. Congress, E-Government Act of 2002.
 
Crowd sourced content that is contributed to World Heritage Encyclopedia is peer reviewed and edited by our editorial staff to ensure quality scholarly research articles.
 
By using this site, you agree to the Terms of Use and Privacy Policy. World Heritage Encyclopedia™ is a registered trademark of the World Public Library Association, a non-profit organization.
 


Copyright © World Library Foundation. All rights reserved. eBooks from Project Gutenberg are sponsored by the World Library Foundation,
a 501c(4) Member's Support Non-Profit Organization, and is NOT affiliated with any governmental agency or department.