World Library  
Flag as Inappropriate
Email this Article

Suprofen

Article Id: WHEBN0009036933
Reproduction Date:

Title: Suprofen  
Author: World Heritage Encyclopedia
Language: English
Subject: Felbinac, Janssen Pharmaceutica, Non-steroidal anti-inflammatory drugs, Ethenzamide, Amfenac
Collection:
Publisher: World Heritage Encyclopedia
Publication
Date:
 

Suprofen

Systematic (IUPAC) name
(RS)-2-[4-(2-thienylcarbonyl)phenyl]propanoic acid
Clinical data
AHFS/Drugs.com
Pregnancy
category
  • US: C (Risk not ruled out)
Legal status
  • Discontinued
Routes of
administration
Oral, eye drops
Pharmacokinetic data
Protein binding 20%
Identifiers
CAS Registry Number  YesY
ATC code M01
PubChem CID:
IUPHAR/BPS
DrugBank  YesY
ChemSpider  N
UNII  YesY
KEGG  YesY
ChEBI  N
ChEMBL  N
Chemical data
Formula C14H12O3S
Molecular mass 260.309 g/mol
 N   

Suprofen is a non-steroidal anti-inflammatory drug (NSAID) developed by Janssen Pharmaceutica[1] that was marketed as 1% eye drops under the trade name Profenal.

Uses

Suprofen was originally used as tablet, but oral uses have been discontinued due to renal effects.[2] It was subsequently used exclusively as a topical ophthalmic solution, typically to prevent miosis during and after ophthalmic surgery.[3] This application has been discontinued as well, at least in the US.[4]

References

  1. ^ DE 2353357 
  2. ^
  3. ^ Guidance for FDA Staff and Industry Compliance Policy Guides Manual, Sec. 460.200
  4. ^ Drugs.com: suprofen ophthalmic


This article was sourced from Creative Commons Attribution-ShareAlike License; additional terms may apply. World Heritage Encyclopedia content is assembled from numerous content providers, Open Access Publishing, and in compliance with The Fair Access to Science and Technology Research Act (FASTR), Wikimedia Foundation, Inc., Public Library of Science, The Encyclopedia of Life, Open Book Publishers (OBP), PubMed, U.S. National Library of Medicine, National Center for Biotechnology Information, U.S. National Library of Medicine, National Institutes of Health (NIH), U.S. Department of Health & Human Services, and USA.gov, which sources content from all federal, state, local, tribal, and territorial government publication portals (.gov, .mil, .edu). Funding for USA.gov and content contributors is made possible from the U.S. Congress, E-Government Act of 2002.
 
Crowd sourced content that is contributed to World Heritage Encyclopedia is peer reviewed and edited by our editorial staff to ensure quality scholarly research articles.
 
By using this site, you agree to the Terms of Use and Privacy Policy. World Heritage Encyclopedia™ is a registered trademark of the World Public Library Association, a non-profit organization.
 


Copyright © World Library Foundation. All rights reserved. eBooks from Project Gutenberg are sponsored by the World Library Foundation,
a 501c(4) Member's Support Non-Profit Organization, and is NOT affiliated with any governmental agency or department.