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Tetrahydrocannabivarin (THCV, THV) is a homologue of tetrahydrocannabinol (THC) having a propyl (3-carbon) side chain. This terpeno-phenolic compound is found naturally in Cannabis, sometimes in significant amounts. The psychoactive effects of THCV in Cannabis preparations are not well characterized.
Similarly to THC, it has 7 double bond isomers and 30 stereoisomers (see: Tetrahydrocannabinol#Isomerism). It is not scheduled by Convention on Psychotropic Substances.
Plants with elevated levels of propyl cannabinoids (including THCV) have been found in populations of Cannabis sativa L. ssp. indica (= Cannabis indica Lam.) from China, India, Nepal, Thailand, Afghanistan, and Pakistan, as well as southern and western Africa. THCV levels up to 53.7% of total cannabinoids have been reported. [1] [2]
THCV has been shown to be a CB1 receptor antagonist, i.e. it blocks the effects of THC.[3]
Tetrahydrocannabinol, Cannabis, Cannabidiol, Canada, Belgium