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Title: Thiq  
Author: World Heritage Encyclopedia
Language: English
Subject: Melanocortin receptor
Publisher: World Heritage Encyclopedia


This article is about the selective MC4 agonist. For the heterocyclic amine, see Tetrahydroisoquinoline.

THIQ' is a drug used in scientific research, which is the first non-peptide agonist developed that is selective for the melanocortin receptor subtype MC4.[1][2] In animal studies, THIQ stimulated sexual activity in rats,[3] but with little effect on appetite or inflammation.[4] This supports possible application of MC4 selective agonists for the treatment of sexual dysfunction in humans,[5] although THIQ itself has poor oral bioavailability and a short duration of action so improved analogues will need to be developed.[6]

See also


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