World Library  
Flag as Inappropriate
Email this Article


Article Id: WHEBN0000435760
Reproduction Date:

Title: Telophase  
Author: World Heritage Encyclopedia
Language: English
Subject: List of MeSH codes (G07), Interphase, Mitosis, Cell cycle, List of MeSH codes (G05)
Collection: Cell Cycle, Mitosis
Publisher: World Heritage Encyclopedia


Telophase (from the Greek τέλος, "end" and φάσις (phásis), "stage") is the final stage in both meiosis and mitosis in a eukaryotic cell.

During telophase, the effects of prophase and prometaphase (the nuclear membrane and nucleolus disintegrating) are reversed. Two daughter nuclei form in each daughter cell, and phosphatases de-phosphorylate the nuclear lamins at the ends of the cell, forming nuclear envelopes around each nucleus.[1] Two theories as to how this happens are:

  • Vesicle fusion – When fragments of the nuclear membrane fuse to rebuild the nuclear membrane
  • Reshaping of the endoplasmic reticulum – where the parts of the endoplasmic reticulum containing absorbed nuclear membrane envelop the nuclear space, reforming a closed membrane.[2]

As the nuclear membranes re-form around each set of chromatids, the nucleoli also reappear. Spindle fibres degenerate. The chromosomes also unwind back into the expanded chromatin that is present during interphase. Telophase accounts for approximately 2% of the cell cycle's duration.

Reappearance of the nuclear membrane and nucleolus: the telophase

Cytokinesis usually occurs at the same time that the nuclear envelope is re-forming, yet they are distinct processes.

In land plant cells, vesicles derived from the Golgi apparatus move to the middle of the cell along a microtubule scaffold called the phragmoplast. This structure directs packets of cell wall materials which coalesce into a disk-shaped structure called a cell plate. The cell plate grows out centrifugally and eventually develops into a proper cell wall, separating the two nuclei.


  1. ^ Molecular Cell Biology. 4th edition. W H Freeman. 2000. pp. Section 13.4. 
  2. ^ Hetzer, Mertin (March 2, 2012). "The Nuclear Envelope". National Center for Biotechnology Information 2 (3): a000539.  

External links

  • Media related to at Wikimedia Commons

This article was sourced from Creative Commons Attribution-ShareAlike License; additional terms may apply. World Heritage Encyclopedia content is assembled from numerous content providers, Open Access Publishing, and in compliance with The Fair Access to Science and Technology Research Act (FASTR), Wikimedia Foundation, Inc., Public Library of Science, The Encyclopedia of Life, Open Book Publishers (OBP), PubMed, U.S. National Library of Medicine, National Center for Biotechnology Information, U.S. National Library of Medicine, National Institutes of Health (NIH), U.S. Department of Health & Human Services, and, which sources content from all federal, state, local, tribal, and territorial government publication portals (.gov, .mil, .edu). Funding for and content contributors is made possible from the U.S. Congress, E-Government Act of 2002.
Crowd sourced content that is contributed to World Heritage Encyclopedia is peer reviewed and edited by our editorial staff to ensure quality scholarly research articles.
By using this site, you agree to the Terms of Use and Privacy Policy. World Heritage Encyclopedia™ is a registered trademark of the World Public Library Association, a non-profit organization.

Copyright © World Library Foundation. All rights reserved. eBooks from Project Gutenberg are sponsored by the World Library Foundation,
a 501c(4) Member's Support Non-Profit Organization, and is NOT affiliated with any governmental agency or department.