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Thenalidine

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Thenalidine

Thenalidine
Systematic (IUPAC) name
1-Methyl-N-phenyl-N-(2-thienylmethyl)piperidin-4-amine
Clinical data
Legal status
?
Identifiers
CAS number  Y
ATC code D04 R06
R06 (combinations)
PubChem
DrugBank
ChemSpider  N
UNII  Y
KEGG  Y
Chemical data
Formula C17H22N2S 
Mol. mass 286.436 g/mol
 N   

Thenalidine is an antihistamine with anticholinergic properties used as an antipruritic drug.[1] It was withdrawn from the US, Canadian, and UK markets in 1963 due to a risk of neutropenia.[2]

References

  1. ^ Getzler, N. A.; Ereaux, L. P. (1959). "Evaluation of thenalidine tratrate (sandostene) in dermatological disorders". Canadian Medical Association journal 80 (6): 445–448. PMC 1830689. PMID 13629433. 
  2. ^ "Thenalidine". DrugBank. 


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