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Title: Thiobarbital  
Author: World Heritage Encyclopedia
Language: English
Subject: CGS-8216, CP-615,003, Heptobarbital, Nealbarbital, Probarbital
Collection: Gabaa Receptor Positive Allosteric Modulators, Thiobarbiturates
Publisher: World Heritage Encyclopedia


Systematic (IUPAC) name
Clinical data
  • ?
Legal status
  • ?
Routes of
Pharmacokinetic data
Bioavailability ?
Metabolism ?
Biological half-life ?
Excretion ?
CAS Registry Number  N
ATC code ?
PubChem CID:
DrugBank  N
ChemSpider  Y
Chemical data
Formula C8H12N2O2S
Molecular mass 200.259

Thiobarbital is a drug which is a barbiturate derivative. It is the thiobarbiturate analogue of barbital.


Thiobarbital synthesis:[1][2]

It is of note that although the drug can be prepared by the above route (cf eg thialbarbital), rxn of barbital with phosphorus pentasulfide constitutes an alternative route to thiobarbital.


  1. ^ Fischer, E.; Dilthey, A. (1904). "Ueber C-Dialkylbarbitursäuren und über die Ureïde der Dialkylessigsäuren". Justus Liebig's Annalen der Chemie 335 (3): 334.  
  2. ^ Carrington, H. C. (1944). "45. The action of phosphorus pentasulphide on barbituric acids". Journal of the Chemical Society (Resumed): 124.  

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