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Title: Thiorphan  
Author: World Heritage Encyclopedia
Language: English
Subject: Racecadotril, Kobret, 6β-Naltrexol-d4, Hemorphin, Naloxonazine
Publisher: World Heritage Encyclopedia


Systematic (IUPAC) name
(±)-2-[(2-benzyl-3-sulfanyl-propanoyl)amino]acetic acid
Clinical data
Legal status
CAS number  N
ATC code ?
ChemSpider  YesY
Chemical data
Formula C12H15NO3S 
Mol. mass 253.32 g/mol

Thiorphan is the active metabolite of the antidiarrheal racecadotril (acetorphan).[1] It prevents the degradation of endogenous enkephalins by acting as an enkephalinase inhibitor.[1]

See also


  1. ^ a b Spillantini MG, Geppetti P, Fanciullacci M, Michelacci S, Lecomte JM, Sicuteri F (June 1986). "In vivo 'enkephalinase' inhibition by acetorphan in human plasma and CSF". European Journal of Pharmacology 125 (1): 147–50.  

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