World Health Organization : Regioinal Office for Africa ; Year 1993 ; Africa Region, Education and Training, Issue 153: Report of the Working Group on Regional Health Learning Materials Development

By World Health Organization

Book Id: WPLBN0000186830
Format Type: PDF eBook
File Size: 0.3 MB
Reproduction Date: 2005

Title:	World Health Organization : Regioinal Office for Africa ; Year 1993 ; Africa Region, Education and Training, Issue 153: Report of the Working Group on Regional Health Learning Materials Development
Author:	World Health Organization
Volume:
Language:	English
Subject:	Health., Public health, Wellness programs
Collections:	Medical Library Collection, World Health Collection
Historic Publication Date:
Publisher:	World Health Organization


Citation APA MLA Chicago Organization, W. H. (n.d.). World Health Organization : Regioinal Office for Africa ; Year 1993 ; Africa Region, Education and Training, Issue 153. Retrieved from http://self.gutenberg.org/

Description
Medical Reference Publication

Excerpt
Introduction Chorionic villus sampling (CVS), introduced in the early eighties, is now an established medical procedure in the first trimester of pregnancy. The global experience would be difficult to evaluate, as hundreds of centers around the world perform CVS, but only 146 have consistently reported their cases to the WHO sponsored CVS registry in Philadelphia. A total of 158,774 CVS have been registered to date, providing a valuable source of data for analysis of pregnancy outcomes following CVS. Because of a few reported clusters of children born with limb anomalies after CVS, a previous WHOEURO 1992 meeting (1) examined collected data on 80 000 cases available at that time and made a statement on the safety of CVS and its use in prenatal diagnosis. Although there was no strong evidence for an increased risk of fetal loss and congenital malformations associated with CVS, it was recommended that follow-up data be collected on the short- and long-term complications of CVS, including limb reduction defects (LRD). A special format for reporting such cases was published to facilitate standardizing data collection and also to re-evaluate previously reported material. Because thcre were not enough data for accurate evaluation of the effect of early CVS, it was recommended that CVS should be performed only after 8 weeks' gestation.

Table of Contents
Table of Contents Introduction .................................................... .., ...................................... 2 Fetal loss rates and prevalence of LRD ................................. .. .................. 2 Fetal loss rate as an indicator of CVS performance .................................. 3 Limb reduction defects .............................................................................. 3 Comparative Pattern Analysis of LRD in the General Population and after CVS ............................................................ 4 Conclusions and Recommendations .................................................... 6 Participants ................................................................................................ 7 References ................................................................................................. 7