Factors Involved in the Cytotoxicity of Kaolinite Towards Macrophages in Vitro

By Davies, Reginald

Book Id: WPLBN0000014032
Format Type: PDF eBook:
File Size: 1.06 MB
Reproduction Date: 2005

Title:	Factors Involved in the Cytotoxicity of Kaolinite Towards Macrophages in Vitro
Author:	Davies, Reginald
Volume:
Language:	English
Subject:	Government publications, United Nations., United Nations. Office for Disarmament Affairs
Collections:	Government Library Collection, Disarmament Documents
Historic Publication Date:
Publisher:	United Nations- Office for Disarmament Affairs (Unoda)


Citation APA MLA Chicago Davies, B. R. (n.d.). Factors Involved in the Cytotoxicity of Kaolinite Towards Macrophages in Vitro. Retrieved from https://self.gutenberg.org/

Description
Government Reference Publication

Excerpt
Excerpt: The prevalence of pneumoconiosis in the British china clay industry is under investigation at our Unit. Sheers (1) examined 553 Cornish china clay workers and found evidence of kaolinosis in 9%. Higher prevalences were found in the dustier occupations of milling, bagging and loading of china clay. Oldham) reporting on a radiological survey of 1676 men in the above industry found that 77.4% were within category 0. 17.9% in category 1, and 4.7% in categories 2 and 3 W). In animal studies, King et al. (4) found that intratracheal injection of kaolin into rats caused only a mild reticulin reaction not comparable with the fibrosis produced by quartz. Attygalle et al. (5) demonstrated that a combination of kaolin and dead tubercle bacilli caused a mainly collagenous reaction leading to well-marked fibrosis, the combined action producing more marked lesions in the lung than either material alone. The fibrogenicity of china clay is currently being examined in inhalation studies using specific pathogen-free Fischer rats at our unit.