Methane Negative Chemical Ionization Analysis of 1,3-Dihydro-5- Phenyl- L,4-Benzodiazepin-2-Ones

By Garland, W. A.

Book Id: WPLBN0000050514
Format Type: PDF eBook:
File Size: 0.4 MB
Reproduction Date: 2005

Title:	Methane Negative Chemical Ionization Analysis of 1,3-Dihydro-5- Phenyl- L,4-Benzodiazepin-2-Ones
Author:	Garland, W. A.
Volume:
Language:	English
Subject:	Government publications, United Nations., United Nations. Office for Disarmament Affairs
Collections:	Government Library Collection, Disarmament Documents
Historic Publication Date:
Publisher:	United Nations- Office for Disarmament Affairs (Unoda)


Citation APA MLA Chicago A. Garlan, B. W. (n.d.). Methane Negative Chemical Ionization Analysis of 1,3-Dihydro-5- Phenyl- L,4-Benzodiazepin-2-Ones. Retrieved from https://self.gutenberg.org/

Description
Government Reference Publication

Excerpt
Introduction: Compounds with the general 1,3-dihydro-5-phenyl- 1,4-benzodiazepin-2-one structure (Table 1) are extensively used in medicine as anxiolytic (Valium, Lihrium, Serax, Ativan, Verstran, Tranxene) , anticonvulsant (Clonopin) and hypnotic (Dalmane, Mogadon, Rohypnol) agents (1). Because of the high potency of these compounds and their large volume of distribution (Z), they are present, following dosing, at relatively low concentrations in blood.