Dna Adduct Formation and Mutation Induction by Nitropyrenes in Salmonella and Chinese Hamster Ovary Cells : Relationships with Nitroreduction and Acetylation

By Heflich, Robert H.

Book Id: WPLBN0000072926
Format Type: PDF eBook:
File Size: 0.6 MB
Reproduction Date: 2005

Title:	Dna Adduct Formation and Mutation Induction by Nitropyrenes in Salmonella and Chinese Hamster Ovary Cells : Relationships with Nitroreduction and Acetylation
Author:	Heflich, Robert H.
Volume:
Language:	English
Subject:	Government publications, United Nations., United Nations. Office for Disarmament Affairs
Collections:	Government Library Collection, Disarmament Documents
Historic Publication Date:
Publisher:	United Nations- Office for Disarmament Affairs (Unoda)


Citation APA MLA Chicago H. Heflic, B. R. (n.d.). Dna Adduct Formation and Mutation Induction by Nitropyrenes in Salmonella and Chinese Hamster Ovary Cells : Relationships with Nitroreduction and Acetylation. Retrieved from https://self.gutenberg.org/

Description
Government Reference Publication

Excerpt
Excerpt: The nitrated pyrenes comprise a group of environmental contaminants which are potent mutagens in the Salmonella reversion assay without exogenous metabolic activation. l-Nitropyrene, which may account for up to 25% of the mutagenic activity in diesel particulate (1-51, produces about 500 revertantsinmole using Salmonella typhimurlum strain TA98 (4-7), while the dinitropyrenes, which account for 30% or more of the mutagenic activity of diesel particulate (81, produce between 29,000 and 275,000 revertants/nmole in the same strain (A-7).