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World Health Organization Note for the Press, Year 2006, No. 18: Male Circumcision Update Ongoing Clinical Trials Are Key to Validating the Link Between Male Circumcision and Protection Against HIV Infection

By Kevin De Cock

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Book Id: WPLBN0000117612
Format Type: PDF eBook:
File Size: 0.1 MB
Reproduction Date: 2005



Title: World Health Organization Note for the Press, Year 2006, No. 18: Male Circumcision Update Ongoing Clinical Trials Are Key to Validating the Link Between Male Circumcision and Protection Against HIV Infection  
Author: Kevin De Cock
Volume:
Language: English
Subject: Health., Public health, Wellness programs
Collections: Medical Library Collection, World Health Collection
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Publisher: World Health Organization

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De Cock, B. K. (n.d.). World Health Organization Note for the Press, Year 2006, No. 18. Retrieved from https://self.gutenberg.org/


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Medical Reference Publication

Excerpt
Toronto - In June 2006, the US National Institutes of Health announced that, following an interim review, two ongoing trials in Uganda and Kenya examining the link between male circumcision and the risk of acquisition of HIV infection in men should be continued. The trials are scheduled to end in July 2007 and September 2007 respectively. Data from these studies will be important in validating findings reported in July 2005 from the Orange Farm Intervention Trial in South Africa, funded by the French Agence Nationale de Recherches sur le SlDA (ANRS), which showed a reduction of 60% or more in the risk of acquiring HIV infection among circumcised men. The interim data from the ongoing Uganda and Kenya trials were reviewed in June 2006 by the Data and Safety Monitoring Board (DSMB), which recommended that the studies continue on the grounds that there were not yet enough data to draw firm conclusions. The DSMB further proposed that an additional interim analysis of data from the two studies take place within the next year. The results of the two ongoing trials will help clarify the relationship between male circumcision and risk of HIV in differing contexts, which is key to determining the reproducibility and application of the Orange Farm findings, noted Dr Kevin De Cock, Director, WHO HIVIAIDS Department. 'While we await these important results, UN partners and others are

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