Airflow, Gas Deposition, And Lesion Distribution in the Nasal Passages

By Morgan, Kevin T.

Book Id: WPLBN0000153717
Format Type: PDF eBook:
File Size: 0.8 MB
Reproduction Date: 2005

Title:	Airflow, Gas Deposition, And Lesion Distribution in the Nasal Passages
Author:	Morgan, Kevin T.
Volume:
Language:	English
Subject:	Government publications, United Nations., United Nations. Office for Disarmament Affairs
Collections:	Government Library Collection, Disarmament Documents
Historic Publication Date:
Publisher:	United Nations- Office for Disarmament Affairs (Unoda)


Citation APA MLA Chicago T. Morga, B. K. (n.d.). Airflow, Gas Deposition, And Lesion Distribution in the Nasal Passages. Retrieved from https://self.gutenberg.org/

Description
Government Reference Publication

Excerpt
Excerpt: Rats and mice are used extensively for inhalation toxicology studies designed to assess the risks or understand mechanisms of diseases in humans. Until recently the nose received much less attention than the lower respiratory tract in inhalation toxicology studies. It was not until 1981 (1) that a detailed procedure for histologic preparation of rodent nasal passages for inhalation toxicology studies was published. Since that time many inhalation studies have been performed, revealing many features of the rodent nasal passages. Simultaneously, there has been fairly extensive research on the physiology, biochemistry, and morphology of the nose of rodents and other laboratory animals. Studies of the nose have also been increased by recent interest in the use of this organ as a route for the delivery of drugs and other pharmaceuticals. The toxicologic pathologist can play an important role in this research process by adequately determining and reporting the nature and location of lesions in the nasal passages of animals in toxicology studies (2).