Prediction and Assessment of the Effects of Mixtures of Four Xenoestrogens

By Payne, Joachim

Book Id: WPLBN0000176754
Format Type: PDF eBook:
File Size: 0.1 MB
Reproduction Date: 2005

Title:	Prediction and Assessment of the Effects of Mixtures of Four Xenoestrogens
Author:	Payne, Joachim
Volume:
Language:	English
Subject:	Government publications, United Nations., United Nations. Office for Disarmament Affairs
Collections:	Government Library Collection, Disarmament Documents
Historic Publication Date:
Publisher:	United Nations- Office for Disarmament Affairs (Unoda)


Citation APA MLA Chicago Payne, B. J. (n.d.). Prediction and Assessment of the Effects of Mixtures of Four Xenoestrogens. Retrieved from https://self.gutenberg.org/

Description
Government Reference Publication

Excerpt
Excerpt: There is considerable concern about the increasing incidence of endocrine-related cancers and deteriorating reproductive health in man and wildlife (1?3). It is apparent that a large number of natural and man-made chemicals have the ability to mimic the action of the endogenous steroid hormone 17(Beta)-estradiol by binding to and activating the estrogen receptor (4,5). At any given time, people are exposed to a multitude of such xenoestrogens, yet research has tended to focus predominantly on the activity of single compounds. The need to assess the effects of mixtures of estrogenic agents is widely acknowledged and considered to be an issue of high priority (6). However, the few mixture studies conducted to date with xenoestrogens have suffered from inadequate theoretical and conceptual foundations or could not be reproduced experimentally in other laboratories [for reviews and comments, see (7?9)].