Human Dna Polymerase : Wrong for the Right Reasons

By United Nations

Book Id: WPLBN0000191717
Format Type: PDF eBook
File Size: 0.1 MB
Reproduction Date: 2005

Title:	Human Dna Polymerase : Wrong for the Right Reasons
Author:	United Nations
Volume:
Language:	English
Subject:	Government publications, United Nations., United Nations. Office for Disarmament Affairs
Collections:	Government Library Collection, Disarmament Documents
Historic Publication Date:
Publisher:	United Nations- Office for Disarmament Affairs (Unoda)


Citation APA MLA Chicago Nations, U. (n.d.). Human Dna Polymerase : Wrong for the Right Reasons. Retrieved from https://self.gutenberg.org/

Description
Government Reference Publication

Excerpt
Excerpt: In a recent collaborative study, Thomas A. Kunkel, director of the NIEHS Environmental Biology Program, NIEHS deputy director Samuel H. Wilson, and Roger Woodgate, an investigator at the National Institute of Child Health and Human Development, report novel findings about DNA repair and genome stability in humans. Woodgates laboratory recently discovered and purified polymerase iota (pol ?), one of a superfamily of DNA polymerases that synthesize short stretches of DNA and are relatively inaccurate?that is, they may allow the A, C, G, or T base moieties to be matched to an incorrect mate (for instance, matching G with T or A, rather than with its proper mate, C). The scientists speculate that these enzymes importance therefore lies in DNA repair and damage-induced mutagenesis, not in DNA replication.