Sport-Caught Fish and Breast Cancer

By United Nations

Book Id: WPLBN0000197171
Format Type: PDF eBook:
File Size: 0.4 MB
Reproduction Date: 2005

Title:	Sport-Caught Fish and Breast Cancer
Author:	United Nations
Volume:
Language:	English
Subject:	Government publications, United Nations., United Nations. Office for Disarmament Affairs
Collections:	Government Library Collection, Disarmament Documents
Historic Publication Date:
Publisher:	United Nations- Office for Disarmament Affairs (Unoda)


Citation APA MLA Chicago Nations, B. U. (n.d.). Sport-Caught Fish and Breast Cancer. Retrieved from https://self.gutenberg.org/

Description
Government Reference Publication

Excerpt
Excerpt: A New Mechanism for Chlorpyrifos? Implicating Serotonin Organophosphate pesticides kill insects by allowing the neurotransmitter acetylcholine to build up at nerve endings. This short-circuits the cholinergic system, which governs involuntary processes. Low organophosphate doses given to rats in utero are associated with neurodevelopmental effects and impaired behavior in adult animals, and in the past, researchers assumed these adverse effects arose from disruption of the cholinergic system. But recently Justin E. Aldridge and colleagues at Duke University Medical Center found that one organophosphate, chlorpyrifos, appears to affect brain development through other, additional mechanisms, and at doses lower than those that perturb the cholinergic system. Now Aldridge and colleagues report that fetal and newborn rats exposed to chlorpyrifos during particular developmental windows undergo changes in their brain serotonin systems that persist into adulthood, possibly contributing to the neurodevelopmental effects of this particular pesticide [EHP 112:148?155].