Effect of Copper and Zinc Status on Susceptibility to Cadmium Intoxication

By Bremner, I.

Book Id: WPLBN0000227745
Format Type: PDF eBook:
File Size: 0.2 MB
Reproduction Date: 2005

Title:	Effect of Copper and Zinc Status on Susceptibility to Cadmium Intoxication
Author:	Bremner, I.
Volume:
Language:	English
Subject:	Government publications, United Nations., United Nations. Office for Disarmament Affairs
Collections:	Government Library Collection, Disarmament Documents
Historic Publication Date:
Publisher:	United Nations- Office for Disarmament Affairs (Unoda)


Citation APA MLA Chicago Bremner, B. I. (n.d.). Effect of Copper and Zinc Status on Susceptibility to Cadmium Intoxication. Retrieved from https://self.gutenberg.org/

Description
Government Reference Publication

Excerpt
Excerpt: It is now widely recognized that the toxicity of metals cannot be considered without due regard being given to dietary composition and the nutritional state of the animal. Increased cadmium intake can cause alterations in the metabolism of copper and zinc in experimental animals and, conversely, the development of certain symptoms of cadmium toxicity may, on occasion, be prevented by dietary copper and zinc supplementation. For example, elevated cadmium intakes in rats, chicks and mice have resulted in increased mortality, poor growth, and anemia (1,2). The growth rate was restored by zinc supplementation and the mortality and anemia reduced by increasing the copper intake. Supplementation with copper also prevented the degeneration of aortic elastin, presumably by restoring the activity of the copper-dependent enzyme lysyl oxidase. Clinical signs of zinc deficiency have been reported in poultry (3) fed on high cadmium diets, but were absent in animals in which the zinc intake had been increased.