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Factors Affecting the in Vitro Dissolution of Cobalt Oxide

By Collier, Clare G.

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Book Id: WPLBN0000004920
Format Type: PDF eBook
File Size: 0.3 MB
Reproduction Date: 2005

Title: Factors Affecting the in Vitro Dissolution of Cobalt Oxide  
Author: Collier, Clare G.
Volume:
Language: English
Subject: Government publications, United Nations., United Nations. Office for Disarmament Affairs
Collections: Government Library Collection, Disarmament Documents
Historic
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Publisher: United Nations- Office for Disarmament Affairs (Unoda)

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Collier, C. G. (n.d.). Factors Affecting the in Vitro Dissolution of Cobalt Oxide. Retrieved from https://self.gutenberg.org/


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Government Reference Publication

Excerpt
Introduction: The purpose of this study was to identify a factor in the dissolving environment that could account for the species differences in translocation rates of nCo from lungs to blood observed after inhalation of cobalt oxide (57030,()1). A simple system was used, and no attempt was made to estimate the magnitude of the dissolution rates in viva from those obtained in vitro. Studies of the factors involved in particle dissolution have established the characteristics of the environment that affect particle dissolution. Of these Factors the most important are the pH, concentration of complexing agents, such as citrate and bicarbonate, and the extent of hydrolysis, absorption, and precipitation (2.3). This study compared the effect of three factors, pH, citrate concentration, and bicarbonate concentration, on the dissolution of J 7 from S7Co3O4T.

 
 



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