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Health Organisation, Malaria Comission; World Health Organization : Organisation Mondiale de la Sante; Serie de Monographies, Issue No. 393: The Measurement of Antibody in Human Malaria Infection by a Formolized Tanned Sheep Cell Haemagglutination Test

By B. Stein

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Book Id: WPLBN0000057578
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Reproduction Date: 2005



Title: Health Organisation, Malaria Comission; World Health Organization : Organisation Mondiale de la Sante; Serie de Monographies, Issue No. 393: The Measurement of Antibody in Human Malaria Infection by a Formolized Tanned Sheep Cell Haemagglutination Test  
Author: B. Stein
Volume:
Language: English
Subject: Health., Public health, Wellness programs
Collections: Medical Library Collection, World Health Collection
Historic
Publication Date:
Publisher: World Health Organization

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Stein, B. B. (n.d.). Health Organisation, Malaria Comission; World Health Organization : Organisation Mondiale de la Sante; Serie de Monographies, Issue No. 393. Retrieved from https://self.gutenberg.org/


Description
Medical Reference Publication

Excerpt
It i.s well. known that an immune response occurs in malaria inf'ections of man and animals However, there have been few methods available to detect and measure humoral antibodies elaborated against the parasite Eaton (1938) described an agglutination t e s t using homologous antigen and the sera of monkeys ckircnicalljr infected or' recovered from Plasniodium knowlesi. Eaton & Coggeshall (1939) demonstrated complement f ixine; antibodies i n monkeys immunized by injections of killed Plasmodium knowlesi antigen They came to the conclusion that such antibodies were g~oup-, not strain-specific and did not confer protection against fwther infection. Sutliff e t a l , (1950) found the complement fixation t e s t w i t h P. krlowlesi valuable in detecting cases where the clinical picture ----- and history indicates malaria but parasitaemia is not demonstrable. More recently the fluorescent antibody technique has been appliea by Tobie Sc Coatney (1961)~ Tobie, Kuvir,, Coatney & Evans (1962), and Voller & Bray (1962).

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