Toxicity and Fetotoxicity of Tcdd, Tcdf and Pcb Isomers in Rhesus Macaques (Macaca Mulatta)

By Mcnulty, Wilbur P.

Book Id: WPLBN0000144976
Format Type: PDF eBook
File Size: 2.1 MB
Reproduction Date: 2005

Title:	Toxicity and Fetotoxicity of Tcdd, Tcdf and Pcb Isomers in Rhesus Macaques (Macaca Mulatta)
Author:	Mcnulty, Wilbur P.
Volume:
Language:	English
Subject:	Government publications, United Nations., United Nations. Office for Disarmament Affairs
Collections:	Government Library Collection, Disarmament Documents
Historic Publication Date:
Publisher:	United Nations- Office for Disarmament Affairs (Unoda)


Citation APA MLA Chicago Mcnulty, W. P. (n.d.). Toxicity and Fetotoxicity of Tcdd, Tcdf and Pcb Isomers in Rhesus Macaques (Macaca Mulatta). Retrieved from https://self.gutenberg.org/

Description
Government Reference Publication

Excerpt
Excerpt: Although toxicological research with nonhuman primates can be formidable because of the expense, scarcity, and complexity of husbandry of the animals, the use of monkeys for investigations with polycblorinated biphenyls and other polyhalogenated polyaromatic compounds offers certain attractive features. Since the sensitivities to and the manifestations of toxicity from these chemicals vary widely in different species of laboratory animals, at least one animal model that is biologically closely related to human beings is highly desirable-with the caveat that close biological relationship is not a guarantee of close toxicological similarity. The large size and long life of monkeys permit studies of long-term exposure, uncomplicated by aging, during which repeated sampling of blood and tissue from individual animals can easily be done. On the other.