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2-Amino-3-carboxymuconic semialdehyde

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2-Amino-3-carboxymuconic semialdehyde

2-Amino-3-carboxymuconic semialdehyde
Identifiers
CAS number 16597-58-3
PubChem 5280673
ChemSpider 7822292 YesY
ChEBI CHEBI:994 YesY
Jmol-3D images Image 1
Properties
Molecular formula C7H7NO5
Molar mass 185.13 g/mol
Density 1.527 g/mL
Boiling point

389 °C, 662 K, 732 °F

Hazards
Flash point 189°C
 YesY (verify) (what is: YesY/N?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

2-Amino-3-carboxymuconic semialdehyde is an intermediate in the metabolism of tryptophan in the tryptophan-niacin catabolic pathway. Quinolinate is a neurotoxin formed nonenzymatically from 2-amino-3-carboxymuconic semialdehyde in mammalian tissues. 2-Amino-3-carboxymuconic semialdehyde is enzymatically converted to 2-aminomuconate via 2-aminomuconic semialdehyde.

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