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Aquayamycin

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Title: Aquayamycin  
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Subject: List of dopaminergic drugs, Alpha-Difluoromethyl-DOPA, Catecholaminergic, D-161, Sercloremine
Collection: Anthraquinone Glycosides, Tyrosine Hydroxylase Inhibitors
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Aquayamycin

Aquayamycin[1]
IUPAC name

(3R,4aR,12bS)-9-[(2R,4R,5S,6R)-4,5-dihydroxy-6-methyloxan-2-yl]-3,4a,8,12b-tetrahydroxy-3-methyl-2,4-dihydrobenzo[a]anthracene-1,7,12-trione

Identifiers
CAS number  YesY
PubChem
ChemSpider  YesY
MeSH
Jmol-3D images Image 1
Properties
Molecular formula C25H26O10
Molar mass 486.47 g/mol
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
 YesY   YesY/N?)

Aquayamycin is an anthraquinone derivative.[2] It is an inhibitor of the enzyme tyrosine hydroxylase.

Saquayamycins (saquayamycins A, B, C and D) are antibiotics of the aquayamycin group found in Streptomyces nodosus cultures broth.[3]

References

  1. ^ Aquayamycin - Compound Summary, PubChem.
  2. ^ Sezaki, M.; Kondo, S.; Maeda, K.; Umezawa, H.; Ono, M. (1970). "The structure of aquayamycin". Tetrahedron 26 (22): 5171–5190.  
  3. ^ Uchida, T.; Imoto, M.; Watanabe, Y.; Miura, K.; Dobashi, T.; Matsuda, N.; Sawa, T.; Naganawa, H.; Hamada, M.; Takeuchi, T.; Umezawa, H. (1985). "Saquayamycins, new aquayamycin-group antibiotics". The Journal of antibiotics 38 (9): 1171–1181.  
Class
Substrate
Oxidoreductase (EC 1)
Transferase (EC 2)
Hydrolase (EC 3)
Lyase (EC 4)
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