This article will be permanently flagged as inappropriate and made unaccessible to everyone. Are you certain this article is inappropriate? Excessive Violence Sexual Content Political / Social
Email Address:
Article Id: WHEBN0026680890 Reproduction Date:
BOH, also known as 3,4-methylenedioxy-β-methoxyphenethylamine, is a drug of the phenethylamine class.[1] It is the β-methoxy analogue of methylenedioxyphenethylamine (MDPEA), and is also more distantly related to methylone. On account of its similarity to norepinephrine, the effects of BOH may be of a purely adrenergic nature.[1]
BOH was first synthesized by Alexander Shulgin.[1] In his book PiHKAL, the dosage range is listed as 80–120 mg, and the duration listed as 6–8 hours. Shulgin reports that BOH causes slight warmth, mydriasis, anorexia, mild nausea, and cold feet, with no psychedelic, entactogen, or euphoriant effects.[1] He gives it a ++ on the Shulgin Rating Scale.[1] Very little is known about the pharmacology, pharmacokinetics, effects, and toxicity of BOH.
* Note that many TCAs, TeCAs, antipsychotics, ergolines, and some piperazines like buspirone and trazodone all antagonize α1-adrenergic receptors as well, which contributes to their side effects such as orthostatic hypotension.
* Note that many atypical antipsychotics and azapirones like buspirone (via metabolite 1-PP) antagonize α2-adrenergic receptors as well.
* Note that MAO-B inhibitors also influence norepinephrine/epinephrine levels since they inhibit the breakdown of their precursor dopamine.
Entactogens: Lophophine