World Library  
Flag as Inappropriate
Email this Article

Ctn-986

Article Id: WHEBN0022570488
Reproduction Date:

Title: Ctn-986  
Author: World Heritage Encyclopedia
Language: English
Subject: Quercetin, List of compounds with carbon numbers 30–39
Collection:
Publisher: World Heritage Encyclopedia
Publication
Date:
 

Ctn-986

CTN-986
Identifiers
CAS number  Y
Jmol-3D images Image 1
Properties
Molecular formula C32H38O20
Molar mass 742.63 g mol−1
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
 N?)

CTN-986 is a glycoside of quercetin found in cottonseeds and cottonseed oil. In a rodent model, it displays some antidepressant-like properties and stimulation of neurogenesis in the hippocampus.[1] The neurogenesis appears to be mediated by activation of the 5-HT1A receptor.[1] Co-administration with the 5-HT1A antagonist WAY-100,635 abolished the effect.[1]

References

  1. ^ a b c Zhang LM, Zhang YZ, Liu YQ, Gong ZH, Zhao YM, Li YF. (2009). "CTN-986, a compound extracted from cottonseeds, increases cell proliferation in hippocampus in vivo and in cultured neural progenitor cells in vitro". Eur J Pharmacol. PMID 19374877. doi:10.1016/j.ejphar.2008.12.052. 


This article was sourced from Creative Commons Attribution-ShareAlike License; additional terms may apply. World Heritage Encyclopedia content is assembled from numerous content providers, Open Access Publishing, and in compliance with The Fair Access to Science and Technology Research Act (FASTR), Wikimedia Foundation, Inc., Public Library of Science, The Encyclopedia of Life, Open Book Publishers (OBP), PubMed, U.S. National Library of Medicine, National Center for Biotechnology Information, U.S. National Library of Medicine, National Institutes of Health (NIH), U.S. Department of Health & Human Services, and USA.gov, which sources content from all federal, state, local, tribal, and territorial government publication portals (.gov, .mil, .edu). Funding for USA.gov and content contributors is made possible from the U.S. Congress, E-Government Act of 2002.
 
Crowd sourced content that is contributed to World Heritage Encyclopedia is peer reviewed and edited by our editorial staff to ensure quality scholarly research articles.
 
By using this site, you agree to the Terms of Use and Privacy Policy. World Heritage Encyclopedia™ is a registered trademark of the World Public Library Association, a non-profit organization.
 


Copyright © World Library Foundation. All rights reserved. eBooks from Project Gutenberg are sponsored by the World Library Foundation,
a 501c(4) Member's Support Non-Profit Organization, and is NOT affiliated with any governmental agency or department.